Not one vomit bag was used on our route through South Dakota and Colorado
Our family recently road-tripped through South Dakota, Wyoming, Colorado, and Nebraska — but beforehand, we made a big announcement. Our third and final embryo transfer was successful, and we’re expecting our second child in November!
To reach this moment, we navigated a suspenseful final round of IVF, a joyous and nauseous first trimester, and our first road trip with Baby #2 (nicknamed Biggler #2). It’s been a hopeful whirlwind. We know pregnancy is far from a guarantee for couples with infertility, let alone the chance to choose how many kids you’ll have. We’ve stumbled and sobbed our way through, but we made it to our goal. We’re still astonished.
As I take on my second trimester, I’m excited to celebrate through my favorite lens: travel. To start, I can share what I’ve learned about mitigating morning sickness, or pregnancy nausea, and enjoying time on the road. Of course, since every pregnancy is unique, it’s always a good idea to ask your doctor if you have questions or concerns before setting off on an adventure.
Setting the Scene: Our Route and My Symptoms

Another exciting announcement inspired the route for our trip. In January, Rilo Kiley — my favorite band — announced a reunion tour, and I lost my mind in a sea of excitement and uncertainty. As you might recall, IVF is the recurring trickster in my travel story, rearing its head repeatedly to create complications and question marks. In this case, the questions came from multiple angles. Would I be pregnant during the entire tour? Would I be pregnant at all? What would the full tour route look like? What venue would be most appropriate for a pregnant concert viewing? Because there was no way I would miss this.
After some trial and error (and an extra pair of tickets bought and sold), we landed on Red Rocks Amphitheatre in Denver. On the way, we would trek through South Dakota to visit Reptile Gardens with our toddler and see the Badlands. It was a grand plan, but not without its obstacles: Namely, constant nausea.
During my first pregnancy, nausea and vomiting were a predictable constant right up until our daughter was born. I expected no less during my second pregnancy, but I wound up with even more discomfort. At my worst, I threw up four times in one day, lost some weight, and went to urgent care for fluids. At that point, the trip was on the line (Jenny Lewis reference intended).
The medications I had taken during my previous pregnancy — Metoclopramide and Famotidine, primarily — were ineffective against my worsening nausea. Remedies like ginger and constant snacking helped, but not nearly enough. However, a couple of weeks before the trip, I finally found a routine that stabilized me and made travel possible.
Central to the plan was Unisom (or doxylamine succinate), a sleep aid that takes the edge off nausea while also, predictably, making you sleepy. To keep my slumbering heart at bay (yes, still intended), I began taking half a pill mid-morning with Vitamin B6 along with another half pill in the late afternoon. This doesn’t eliminate my nausea, but it does help quite a bit.
With Unisom as my shield, we hit the road in mid-May and headed off toward spectacular views (last one). Here’s what went well and what I would have done differently.
What I Did Right

Ate a High-Protein Hotel Breakfast
As a vegetarian, eggs are one of my go-to sources of protein. And they’ve been a lifesaver during my second pregnancy. There is evidence suggesting protein is easier to digest in the first trimester, and that choosing high-protein options can reduce nausea. In my experience, this has been true. When we planned our trip, we only booked hotels with breakfast, and we looked for photos with eggs. Protein aside, we prioritized breakfast and snacks throughout the trip. It can be tempting to hit the road early and skip a sit-down meal, or travel light without messy food in the car. But pregnancy nausea is often exacerbated by an empty stomach. We didn’t take that chance.
Enjoyed the Outdoors (w/o Overdoing It)
I’m so glad we chose an outdoor venue to see Rilo Kiley, let alone the gorgeous and legendary Red Rocks Amphitheatre. The fresh air helped keep my nausea at bay, even in the surprisingly chilly temperatures we encountered. During the first half of our trip, heat was our main concern, as temperatures neared 100 degrees. Despite the heat, I have no regrets about our outdoor explorations at Reptile Gardens, Badlands National Park, and Dinosaur Ridge. We made sure to wear hats, apply sunscreen, and take frequent breaks. With these precautions in place, I believe the exercise, fresh air, and change of scenery helped keep my stomach steady.
Packed Comfortable Clothes
I had no qualms about breaking into my maternity clothes even before Week 15, when we took off. Our trip involved more than one long leg of driving, and I spent those hours in the comfort of soft, stretchy maternity shorts. I also packed lightweight, flowy dresses, a maternity skort, comfortable bras, and an assortment of short-sleeved shirts. I do wish I had packed warmer clothes for the concert but, otherwise, this wardrobe was spot on.
What I Would Do Differently

Drink More Water
This is a constant struggle for me during pregnancy. Water triggers my nausea — especially more than just a sip or two at a time. But dehydration is a serious concern. On the road, we ended up facing a dehydration-related scare. I was tipped off by a symptom that turned out to be pretty common during travel, even in early pregnancy: swelling ankles and feet. At the time, my mind went straight to the pre-eclampsia I previously experienced. We took my blood pressure at a Wal-Mart en route, and it came back pretty high. My OB’s office assured me that it was too early to worry about pre-eclampsia, and they advised me to watch for worsening symptoms. Luckily, the issue didn’t worsen, and it mostly cleared up by the time I got home, although I’m still monitoring my blood pressure. Dehydration can impact blood pressure, so I’m doing my best to avoid it. To keep fluids down on the road, I focused on beverages that triggered my nausea the least: ice cold water through a straw, 7Up Zero, and orange juice, among others. Looking back, I also wish I had traveled with my own blood pressure cuff (ideally, calibrated at the doctor’s office).
Plan Short Driving Days
I come from a family of jam-packed travel itineraries. But with a toddler, my goal is usually to rein in this habit. This was especially true planning a trip during pregnancy. We did a pretty good job balancing our daily activities, but in order to save money on hotels, we ended up planning a couple of days with 8+ hours of driving. This turned out to be excessive. Looking back, I would bite the bullet while pregnant and spend a little extra on hotels to avoid at least one of those long days. Six hours of driving seems to be the ideal limit for us.
Make Time for the Pool
I love being in the water, so I’m very at home in a hotel pool. But on this trip, we simply didn’t plan enough day time at the hotel to relax. I was usually too tired or nauseated at the end of the day to take a dip. Swimming can be a great form of exercise in pregnancy (as long as you’re already acclimated). And time in the water is relaxing. In the future, I’ll set aside more time to enjoy this amenity with my toddler.